Table 2. Parameter values of the I_L–V curve fits.

	n	C (pF)	Gmax (nS)	V1/2,G (mV)	kG (mV)	Vrev (mV)	Imax (nA)
Control	32	296.5 ± 19.2	58.8 ± 4.5	12.7 ± 1.2	5.2 ± 0.2	71.4 ± 2.0	−2.47 ± 0.18
MβCD	20	224.4 ± 20.3*	34.5 ± 2.9**	29.0 ± 1.7**	6.7 ± 0.3**	73.8 ± 1.9	−0.89 ± 0.15**
MβCD + cholesterol	9	306.4 ± 35.9	54.4 ± 4.4	15.9 ± 2.1	6.1 ± 0.3*	74.2 ± 3.5	−2.26 ± 0.27

All the parameters were calculated as described in Methods. C is the membrane capacitance of the cell, G_max is the maximum conductance for the peak current, V_1/2,G is the potential that elicits the half-maximum increase in conductance, k_G is a steepness factor, I_max, is the peak of the I_L–V curve fit and V_rev the corresponding potential. Data are given as mean ±s.e.m. and were obtained by fitting the data from n fibres in each group. Asterisks indicate values which are significantly different (*P < 0.05; **P < 0.001) from the corresponding control values (Mann-Whitney test).