Figure 4. Brachial artery flow-mediated dilatation.
Brachial artery flow-mediated dilatation is shown (normalized for the hyperaemic flow stimulus) in young and older sedentary men and older endurance exercise-trained men at baseline, after acute ascorbic acid infusion, and after 30 days of ascorbic acid supplementation. A, percentage change in diameter divided by percentage change in blood flow; B, absolute (mm) change in diameter divided by absolute (ml min−1) change in blood flow. Mean ±s.e.m. values are shown. Filled bars: young sedentary; open bars: older sedentary; and hatched bars: older endurance trained. Acute = postinfusion; Chronic = end of oral supplementation. * P < 0.01 versus young and older trained groups.