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A, control traces from Kv1.4ΔN. B, Kv1.4ΔN with 100 μm quinidine. C, Kv1.4[V561A]ΔN. D, Kv1.4[V561A]ΔN in the presence of 500 μm quinidine. In both cases, quinidine depressed the peak open current and speeded the rate of inactivation. Dotted lines indicate zero current.
