Figure 2. Effects of steroids on mean durations.

The arithmetic mean open times (A), closed times (B) and calculated P_open (C) in clusters elicited by 50 μm GABA in the presence of various concentrations of ACN (•) or B285 (▵) are shown. The curves show the fit of the equation Y([steroid]) =Y₀+ (Y_max–Y₀)[steroid]/([steroid]+ EC₅₀) for data obtained in the presence of ACN (continuous lines) and B285 (dashed lines). (The continuous line in B shows the mean closed time in the presence of ACN; no fit was performed to these data.) The dotted lines show the mean values for data obtained using 50 μm GABA in the absence of steroid. Values for the fit parameters are given in Table 1.