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. 2004 Feb 6;556(Pt 2):495–506. doi: 10.1113/jphysiol.2003.058628

Figure 3. Spontaneous currents (STICs).

Figure 3

A shows a record from cell firing STICs when held under voltage clamp at −60 mV. Note that the STICs were irregular in shape and amplitude. B, effect of A9C on STICs. C, summary of the effect of A9C (1 mm) on mean STIC amplitude in 6 cells. D, effect of niflumic acid on STICs. E, summary of the effect of niflumic acid (100 μm) on mean STIC amplitude in 5 cells. F, reversal potentials (Erev) of spontaneous currents in a cell subjected to ramp protocols (for details see text). Substitution of external Cl− with glutamate (Glut), an impermeant anion, shifted Erev in the positive direction, while substitution with I−, a more permeant anion than Cl−, shifted Erev in the negative direction. (Displayed data were uncorrected for junction potentials.)