Table 1.

Measured haemodynamic parameters of non-transgenic (NTG) and α-TM DM transgenic (TG) hearts

	NTG male hearts	male hearts TM DM	Percentage change versus NTG
Working heart	(N = 5, 50)	(N = 2, 20)
Heart rate (beats min−1)	405 ± 1	404 ± 1	Paced n.s.
+dP/dt (mmHg s−1)	6014 ± 167	4863 ± 170	−19**
−dP/dt (mmHg s−1)	4469 ± 170	3530 ± 186	−21**
LVP (mmHg)	109 ± 3	105 ± 2	n.s.
Time to peak pressure (ms)	46 ± 1	42 ± 1	−9*
τ	20 ± 1	27 ± 7	+35*

Values are mean ±s.e.m.

^*P≤ 0.05,

^**P≤ 0.001, transgenic versus control, Student's unpaired t test.LVP, left ventricular pressure; N; number of mouse hearts.