Table 2.

Characteristics of fast synaptic inputs in myenteric S-neurons that underlie EJP generation in circular muscle

EJP amplitude in CM (mV)			FEPSP duration in S-neurons (ms)			Latency between end of FEPSP burst and onset of EJP (ms)
Mean ± S.E.M	Range	n	Mean ± S.E.M	Range	n	Mean ± S.E.M	Range	n
12.4 ± 0.45*	3–27	26	89.0 ± 5.2	4–284	26	100.6 ± 4.4	11–271	26

Table 2 shows the characteristics of fast synaptic inputs recorded from a population of myenteric S-neurons which showed time-locked FEPSPs prior to the onset of EJPs in the CM layer. The mean duration of a burst of fast EPSPs (88 ms) was the time in which a discrete discharge of FEPSPs occurred in S-neurons immediately prior to the activation of an EJP in the CM layer. The mean latency between the onset of an EJP in the CM and the end of a fast synaptic burst in an S-neuron was ∼100 ms, which is highly consistent with the time courses known for the activation of second messenger systems known to generate a junctional current in gastrointestinal smooth muscle.