Figure 6. Type-1 inspiratory neurones (Rekling et al. 1996).
Ai, control activity. Aii, burst-triggered average activity (n= 8 control cycles); note preinspiratory depolarization (arrow). Aiii, delayed excitation consistent with an IA-like current (arrow) was elicited by step depolarization to −30 mV from −85 mV. Bi, these neurones were strongly hyperpolarized during mid-expiratory inflation (shaded bar). Bii, by applying bias currents, inflation-induced hyperpolarization (shaded bar) could be reversed. ΔV, difference between holding membrane potential and membrane potential during inflation (double-headed arrow). The reversal potential (i.e. ΔV= 0) was calculated to be −66 mV.