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. 2004 May 6;558(Pt 3):883–896. doi: 10.1113/jphysiol.2003.056945

Figure 5. Effect of pressure on diameter of endothelium-intact arteries from fetal and adult sheep during inhibition of endothelium-derived substances.

Figure 5

Changes in diameter of endothelium-intact arteries in physiological salt solution (PSS; □) compared to responses in NG.-nitro-L-arginine-methyl ester (l-NAME, •), indomethacin (▴), l-NAME + Indo (○), and Indo +l-NAME (Δ) from 95 days gestation fetal (A and D, n = 14), 140 days gestation fetal (B and E; n = 12), and non-pregnant adult (C and F; n = 12) sheep. In all experiments, arteries were exposed to drug solutions for 20 min before determining responses to pressure. Values are means ± s.e.m. *P < 0.05 compared to PSS response, †P < 0.05 compared to l-NAME response, by ANOVA.