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. 2004 Mar 5;557(Pt 1):59–75. doi: 10.1113/jphysiol.2004.061291

Table 2. OGB-5N transient parameters and peak [Ca2+] for normal and mdx muscle fibres in the absence of EGTA.

F/F)peak Peak [Ca2+] (μm) tp (ms) FDHM (ms) τ1 (ms) τ2 (ms) Aslow/Afast
Normal FDB 1.1 ± 0.02 6.0 ± 0.1 2.1 ± 0.1 8.0 ± 0.5 2.3 ± 0.1 37 ± 3 1.3 ± 0.1
mdx FDB 0.64 ± 0.04 3.3 ± 0.2 2.5 ± 0.1 48 ± 6 3.0 ± 0.4 113 ± 18 2.5 ± 0.3

For experiments, fluorescence transient parameters and peak [Ca2+] were obtained from n= 5 FDB fibres from 2 normal mice and n= 11 fibres from 2 mdx mice. All transients were obtained with 5 mm total [Mg2+].

Statistical significance between normal and mdx FDB fibres (P < 0.05);

statistical significance between normal and mdx FDB fibres (P < 0.0001)