Figure 7. The actions of purinergic receptor agonists and antagonists and carbachol on intracellular [Ca²⁺] and membrane currents in suburothelial myofibroblasts.

A, effects of α,β-methylene-ATP (ABMA) and ATP (100 μm). B, actions of 100 μm ATP and 30 μm UTP. C, actions of 100 μm ATP and 30 μm ADP. D, ATP Ca²⁺ transients in the presence of the P2Y₁ receptor antagonist MRS2179 (30 μm). E, ATP-induced Ca²⁺-transients in the presence of carbachol (100 μm). All agents added where indicated by the horizontal bars; cells voltage-clamped at −60 mV with Cs⁺-filled pipettes.