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. 2004 Apr 2;557(Pt 2):635–643. doi: 10.1113/jphysiol.2004.062984

Figure 1. Ipsilateral and contralateral knee joint diameters.

Figure 1

A, ipsilateral knee joint diameter in AIA. Diameter increased significantly in the vehicle-treated group (•) (P < 0.0001, one-way ANOVA). Both SC-236 (▴) and indomethacin (▪) significantly decreased swelling compared to vehicle-treated animals (P = 0.0001, two-way ANOVA). Knee joint diameter in control non-inflamed animals (○) did not significantly change with time (P = 0.138; n = 5–6; one-way ANOVA). B, contralateral knee joint diameter in AIA. Diameter increased significantly in the vehicle-treated AIA group (•) compared to the control non-inflamed group (P = 0.0001, two-way ANOVA). Both SC-236 (▴) and indomethacin (▪) decreased knee joint diameter by a magnitude proportionate to that of the ipsilateral knee (both P = 0.0001, two-way ANOVA, compared to untreated group). Control non-inflamed values (○) did not significantly change with time (P = 0.5; n = 5; one-way ANOVA).