Figure 3. Initial intracellular inorganic ion concentrations do not influence eventual stable values of V_c or E_m.

A, the starting conditions of three cells used as examples. The model was initiated with the intracellular organic anion concentration identical to that eventually reached in Fig. 1, but with three arbitrary and sharply different intracellular inorganic ion concentrations. Note that none of the cells were initially isotonic to the extracellular fluid. B, the final stable values reached after a 5-h modelling period. Variation in the initial intracellular inorganic ion concentrations has no influence on final stable values of V_c, E_m, [Na⁺]_i, [K⁺]_i, [Cl⁻]_i or [X⁻]_i.