Figure 2. Vestibulo-ocular reflex.

A, eye movements evoked during sinusoidal head rotations at 0.4 and 2.0 Hz for a control mouse and an IsK^−/− mouse. B, mean gain and phase plots of the vestibulo-ocular reflex evoked by 0.2–2.0 Hz rotations in the dark. In normal mice, gain increased linearly with frequency while phase lag decreased with frequency. Responses were the same for stimuli with maximal velocities of 6 or 20° s⁻¹. The VOR gain of IsK^−/− mice was zero for all frequencies and both velocities.