Table 1.
Comparison of single spike parameters in control and 2 m+
| Spike parameters | Units | Control | Co2+ | Wash | t test |
|---|---|---|---|---|---|
| Width at 0 mV | ms | 1.2 ± 0.1 | 1.2 ± 0.1 | 1.1 ± 0.1 | n.s. |
| Width at −30 mV | ms | 2.3 ± 0.2 | 2.4 ± 0.2 | 2.5 ± 0.2 | n.s. |
| Amplitudea | mV | 95.2 ± 3.0 | 90.5 ± 2.9 | 86.3 ± 2.7 | n.s. |
| AHP, maximumb | mV | 68.1 ± 1.2 | 69.2 ± 1.1 | 69.6 ± 1.1 | n.s. |
| AHP, at 40 msc | mV | 67.1 ± 1.0 | 67.8 ± 0.7 | 68.6 ± 0.9 | n.s. |
a
The spike amplitude was measured from a membrane potential of −70 mV.
b
The largest after-hyperpolarization (AHP, maximum) was measured within the first 8–15 ms after beginning of the spike.
c
The second measurement of AHP was 40 ms after the beginning of the spike. Data from 10 neurones. Student's paired t test was used to compare control parameters with those obtained in Co2+. n.s., non-significant difference with P > 0.25.