Skip to main content
. 2004 Jul 29;560(Pt 1):51–62. doi: 10.1113/jphysiol.2004.070292

Figure 3. TASK-1 mutant K70E has increased zinc sensitivity.

Figure 3

A, representative TASK-1 K70E control currents and currents in 100 μm zinc following 200 ms step changes in voltage, in 10 mV increments, from −100 to +80 mV. Arrows indicate zero current. B, zinc concentration–response curves for WT TASK-1 (▴), WT TASK-3 (•) and TASK-1 K70E (▪) shows the increase in zinc efficacy in TASK-1 K70E compared to WT TASK-1. C, bar chart of relative effect of 100 μm zinc on WT TASK-3, TASK-3 E70K, WT TASK-1 and TASK-1 K70E currents.

HHS Vulnerability Disclosure