Skip to main content
. 2004 Aug 12;560(Pt 2):439–450. doi: 10.1113/jphysiol.2004.066035

Figure 4. Two phases of exocytosis.

Figure 4

A, superimposed capacitance jumps in response to 4, 25 and 100 ms depolarizations (arrow). B, average capacitance increases (ΔCm) are plotted against the time of depolarization to −20 mV (▴) and to −50 mV (•). The data for depolarizations up to 500 ms were fitted (dashed lines) with the equation: δCm = A(1 –exp(−t/τ))n + st, where A, τ and s were dependent variables and n was fixed to be the same for depolarizations to either potential (n = 4.8, A−20 = 209 fF, τ−20 = 2.7 ms and s−20 = 1.1 fF ms−1; A−50 = 213 fF, τ−50 = 5.5 ms and s−50 = 0.14 fF ms−1). Dotted lines indicate fitted curve without the linear term. The times to reach 90% of maximal amplitude at −20 and −50 mV were 7.7 and 21.1 ms, respectively. C, linear slow component is long lasting. Same data set and fits as in B but shown on an expanded time scale. The fitted curves from B were extrapolated to 5 s.