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. 2004 Sep 23;561(Pt 1):133–147. doi: 10.1113/jphysiol.2004.071241

Figure 5. Effect of PKC inhibitors on long-term insulin secretion.

Figure 5

A, islets were incubated for 60 min with 40 mm KCl or 20 mm glucose in the presence (filled column) or absence (open column) of 1 μm Gö-6976. B, islets were incubated for 60 min with 40 mm KCl or 20 mm glucose in the presence (filled column) of 75 μm Antp-PKC19–31 or 75 μm Antp (stippled column) or absence of either of them (open column). C, islets were incubated for 60 min with 40 mm KCl or 20 mm glucose in the presence of 75 μm Antp-PKC149–164 (filled column) or 75 μm Antp (stippled column) or absence of either of them (open column). Values are the means ± s. e.m. for 10 experiments. *P < 0.01 versus no inhibitor.