Table 2.
Comparison of anatomical properties of MCs
| Reconstructed MCs | |||||
|---|---|---|---|---|---|
| Anatomical properties | Total MC (n = 24) | MC in LII/III (n = 5) | MC in LIV (n = 7) | MC in LV (n = 5) | AMC in LII/III3 (n = 5) |
| Axonal | |||||
| Bouton/cell (BT)(mean ±s.d.) | 3845 ± 1584 | 2880 ± 948 | 3146 ± 1258 | 3592 ± 1952 | 5302 ± 1527* |
| Bouton density (BD)(boutons/μm) (mean ±s.d.) | 0.219 ± 0.047 | 0.197 ± 0.028 | 0.217 ± 0.038 | 0.173 ± 0.051 | 0.272 ± 0.037* |
| Maximum axonal branch angle (MABA, deg) (mean ±s.e.m.) | 77 ± 1 | 83 ± 1 | 78 ± 1 | 81 ± 4 | 74 ± 1* |
| Planar axonal branch angle(MABA, deg) (mean ±s.e.m.) | 54 ± 1 | 58 ± 1 | 55 ± 1 | 57 ± 4 | 50 ± 1* |
| Axon segment length(ASL, μm) (mean ±s.e.m.) | 48 ± 3 | 43 ± 6 | 38 ± 2 | 53 ± 8 | 61 ± 9 |
| ASD bouton no. (no. bouton/ASD unit) (mean ±s.e.m.) | 275 ± 23 | 245 ± 25 | 222 ± 10 | 424 ± 85 | 249 ± 11 |
| Axon Sholl distance(ASD) (μm) (mean ±s.e.m.) | 285 ± 19 | 259 ± 24 | 236 ± 6 | 403 ± 78 | 292 ± 32 |
| Maximum axonal branch order(ABO) (mean ±s.d.) | 29.7 ± 10.1 | 30 ± 11 | 24 ± 5 | 44 ± 9 | 29 ± 8 |
| Axonal segments/cell(SEG) (mean ±s.d.) | 365 ± 139 | 340 ± 120 | 379 ± 133 | 426 ± 241 | 352 ± 95 |
| Total axonal length (μm)(mean ±s.d.) | 17813 ± 5535 | 14932 ± 5725 | 14061 ± 3368 | 19695 ± 6795 | 19272 ± 3419 |
| Boutons in layer I per cell(%) (mean ±s.d.) | — | 56 ± 20% | 18 ± 7%†‡ | 36 ± 12% | — |
| Dendritic | |||||
| Average length of dendritic tree(ALDT, μm) (mean ±s.e.m.) | 1504 ± 172 | 2103 ± 282 | 1093 ± 185† | 1898 ± 548 | 1169 ± 368 |
| Total dendritic length (μm)(mean ±s.d.) | 3320 ± 1111 | 3252 ± 1027 | 2969 ± 736 | 4348 ± 1328 | 2630 ± 774 |
| Diameter of dendritic cluster (horizontal, μm) (mean ±s.d.) | 273 ± 88 | 212 ± 64 | 267 ± 88 | 364 ± 41* | 200 ± 29 |
| Diameter of dendritic cluster (vertical, μm) (mean ±s.d.) | 490 ± 129 | 582 ± 122 | 362 ± 65†‡ | 499 ± 62 | 552 ± 65 |
| Dendritic branch order (DBO) (mean ±s.e.m.) | 6.5 ± 0.4 | 5.8 ± 0.7 | 6.1 ± 0.3 | 8.7 ± 1.4 | 5.4 ± 0.8 |
| Maximum dendritic branch order(Max. DBO) (mean ±s.d.) | 9.5 ± 2.5 | 8.8 ± 0.5 | 7.9 ± 1.7 | 10.5 ± 3.4 | 9.5 ± 2.5 |
| Dendritic Sholl distance (DSD) (μm)(mean ±s.e.m.) | 128 ± 6 | 142 ± 14 | 108 ± 4†‡ | 133 ± 13 | 129 ± 15 |
| Dendritic segment length (DSL)(μm) (mean ±s.e.m.) | 50 ± 2 | 55 ± 7 | 48 ± 3 | 51 ± 4 | 46 ± 4 |
| Maximum dendritic branch angle (MDBA)(deg) (mean ±s.e.m.) | 59 ± 2 | 61 ± 8 | 61 ± 3 | 64 ± 6 | 48 ± 4 |
| Planar axonal branch angle (PDBA)(deg) (mean ±s.e.m.) | 43 ± 2 | 44 ± 5 | 46 ± 2 | 47 ± 6 | 39 ± 3 |
| Number of dendrites/cell (mean ±s.d.) | 3.6 ± 1.3 | 3.8 ± 1.0 | 3.6 ± 1.1 | 2.5 ± 0.6 | 4.0 ± 1.4 |
†
P < 0.05, significant comparison between MC in Layer II/III and MC in Layer IV
‡
P < 0.05, significant comparison between MC in Layer IV and MC in Layer V
*
P < 0.05, significant comparison between MC and AMC (atypical MC) in Layer II/III.