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. 2004 Sep 30;561(Pt 2):485–498. doi: 10.1113/jphysiol.2004.070490

Figure 7. Properties of sIPSCs in ischaemia recorded using gramicidin perforated patch-clamping.

Figure 7

A, recording from a CA1 pyramidal neurone at −33 mV showing the increase in spontaneous IPSCs, and the development of an outward current, when ischaemia solution was applied; an AD occurred a few seconds after the end of the trace, but is not shown in order to display the pre-AD current on a larger scale. B, expanded regions of 1 s duration from the trace in A. Pre-ischaemia represents events before ischaemia, upward deflections are sIPSCs (marked with dots). All other traces show events during ischaemia, with the times stated representing time elapsed since the ischaemic solution was applied. C–F, plots of frequency (C), amplitude (D), 10–90% rise time (E) and decay time of sIPSCs during ischaemia (F); points represent 30 s bins of events, averaged over 5 cells.