Figure 7. Effect of coil position and stimulus intensity on responses to rTMS.
A, conditioning effects of 5 Hz rTMS over SMA at 110% AMT vs. sites 3 cm anterior or posterior to SMA on MEP amplitudes 5–10 and 15–20 min after the end of rTMS. Data are given as percentages of pre-rTMS baseline values in the right relaxed FDI muscle of 7 subjects. Note that because the experiments examining differences in the effects from the three stimulations were performed on different days, the amplitudes of the baseline MEPs varied slightly (baseline MEPs before rTMS over SMA, 1.19 ± 0.14 mV; 3 cm anterior, 1.14 ± 0.11 mV; 3 cm posterior, 1.02 ± 0.13 mV). B, conditioning effects of 5 Hz rTMS over SMA at 110% AMT vs. a site 2 cm lateral to SMA on MEP amplitudes relative to the baseline values (baseline MEPs before rTMS over SMA, 1.16 ± 0.19 mV; 2 cm lateral, 1.22 ± 0.16 mV) in the right relaxed FDI muscle of 4 subjects. C, conditioning effects of 5 Hz rTMS over SMA at 110% AMT vs. 100% AMT on the percentage changes of the MEP amplitude relative to the baseline values (110% AMT, 1.18 ± 0.12 mV; 100% AMT, 1.09 ± 0.1 mV) in the right relaxed FDI muscle of 8 subjects. Error bars are s.e.m. Asterisks denote a significant change relative to baseline.