Table 2.

Rest and exercise haemodynamic responses during saline and l-NMMA infusion

	Heart Rate		Systolic blood pressure		Diastolic blood pressure		Pulse pressure
	Saline	l-NMMA	Saline	l-NMMA	Saline	l-NMMA	Saline	l-NMMA
Baseline	66 ± 2	74 ± 2	117 ± 3	116 ± 3	75 ± 2	76 ± 2	42 ± 2	40 ± 2
Handgrip
Rest	66 ± 2	72 ± 2	122 ± 3	120 ± 3	78 ± 2	82 ± 2	43 ± 2	38 ± 1
1.25 kg	67 ± 2	71 ± 2	125 ± 4	123 ± 3	82 ± 2*	85 ± 2*	43 ± 3	38 ± 2
2.5 kg	70 ± 3*	73 ± 2	128 ± 4*	127 ± 3*	83 ± 2	84 ± 1	45 ± 3	43 ± 3
3.75 kg	71 ± 2	75 ± 2*	135 ± 4*	133 ± 4*	87 ± 2*	90 ± 2*	48 ± 3	44 ± 3
Cycle
Rest	71 ± 2	76 ± 2	125 ± 4	126 ± 3	84 ± 3	86 ± 2	40 ± 2	40 ± 2
60 W	108 ± 4*	110 ± 4*	156 ± 5*	159 ± 5*	83 ± 3	86 ± 3	73 ± 4*	73 ± 4*
80 W	121 ± 5*	124 ± 5*	177 ± 6*	181 ± 6*	83 ± 3	87 ± 3	94 ± 5*	94 ± 5*
120 W	138 ± 6*	138 ± 6*	196 ± 4*	201 ± 5*	81 ± 4	84 ± 4	123 ± 8*	117 ± 5*

Values are mean ± s.e.m. Cycle exercise had a significantly greater effect on the magnitude of change in HR, SBP and PP than handgrip exercise under both saline and l-NMMA conditions (all P < 0.001, ANOVA).

^*Significantly different from previous workload (P < 0.05).