Figure 2. Effect of physical inactivity on 2-DOG uptake into isolated epitrochlearis muscle under basal (no added insulin), submaximal insulin-stimulated (60 μU ml⁻¹), and maximal insulin-stimulated (2 mU ml⁻¹) conditions.

Groups had wheels locked for 5 h (WL5), 29 h (WL29), or 53 h (WL53) after 3 weeks of voluntary wheel running, or were sedentary (SED) without running wheels. Columns are mean ± s.e.m.* Significantly different from groups without an asterisk within the same insulin concentration (ANOVA, P≤ 0.05). n = 15–16 in each group for basal and 7–8 in each group for both insulin concentrations.