Experimental traces from an anaesthetized, neuromuscular-blocked and atenolol-pretreated rat illustrating the effects on blood pressure (BP), heart rate (HR), integrated renal nerve activity (IRNA), and integrated phrenic nerve activity (IPNA) evoked by stimulation of cardiopulmonary afferents with intra-atrial phenylbiguanide (PBG; 2 μg) before, and 5 min and 45 min following SB-269970 (100 μg kg−1, intracisternal, i.c.).