Table 1.

Baseline values of mean arterial pressure (MAP), R-R interval, integrated renal (IRNA) and integrated phrenic nerve activity (IPNA) for all cardiopulmonary reflex experimental groups (protocol 1) in anaesthetized, neuromuscular-blocked and atenolol-pretreated rats

		MAP (mmHg)			R-R interval (ms)			IRNA (% of control)		IPNA (% of control)
Experimental group	n	Control	5 min	15 min	Control	5 min	15 min	5 min	15 min	5 min	15 min
Saline
10 μl	5	112 ± 3	116 ± 5	118 ± 5	180 ± 7	175 ± 7	173 ± 7†	96 ± 15	99 ± 18	116 ± 13	121 ± 10
SB-269970
30 μg kg−1	5	113 ± 10	110 ± 11	114 ± 10	177 ± 4	175 ± 5	173 ± 5	99 ± 2	103 ± 4	131 ± 18	123 ± 21
100 μg kg−1	5	120 ± 6	119 ± 10	126 ± 6	182 ± 3	179 ± 3	179 ± 3	102 ± 4	103 ± 5	143 ± 18	88 ± 18*
300 μg kg−1	5	111 ± 9	116 ± 14	131 ± 16	187 ± 5	183 ± 3	175 ± 2†	104 ± 4	115 ± 7	56 ± 9*	24 ± 12**
SB-656104
Vehicle 10 μl	5	107 ± 2	117 ± 1†	118 ± 2†	190 ± 4	186 ± 5	184 ± 5	100 ± 10	129 ± 29	88 ± 10	114 ± 23
100 μg kg−1	5	105 ± 6	115 ± 9	128 ± 8	187 ± 4	185 ± 4	180 ± 4	145 ± 40	139 ± 49	77 ± 8	144 ± 38
WAY-100635
100 μg kg−1	5	115 ± 3	118 ± 4	118 ± 3	170 ± 2	170 ± 2	165 ± 2	95 ± 4	107 ± 5	93 ± 26	87 ± 29

^*P < 0.05

^**P < 0.01 compared to vehicle;

^†P < 0.05 compared to baseline control.