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. 2004 Dec 20;563(Pt 1):265–274. doi: 10.1113/jphysiol.2004.078212

Table 2.

AVP, CRH and GR mRNA in the PVN and POMC mRNA levels in the anterior pituitary for oil-SHOVX, oil-OVXE2, TP-SHOVX and TP-OVXE2 female rats (Mean ±s.e.m, n = 7–8)

Treatment group AVP mRNA (%±s.e.m. of Oil-SHOVX controls) CRH mRNA (%±s.e.m. of Oil-SHOVX controls) GR mRNA (%±s.e.m. of Oil-SHOVX controls) POMC mRNA (%±s.e.m. of Oil-SHOVX controls)
Oil-SHOVX 100 (9) 100 (12) 100 (9) 100 (13)
Oil-OVXE2 101.2 (11) 97.2 (13) 96.3 (7) 114 (15)
TP-SHOVX 65.4 (8)* 51.5 (10)***†† 150.9 (8)** 47.3 (10)***†††
TP-OVXE2 96.3 (11) 90 (14) 114.4 (8) 89.5 (14)

TP-SHOVX rats demonstrated significantly lower levels of AVP, CRH and POMC mRNA compared to the remaining groups and significantly greater levels of PVN GR mRNA compared to oil-treated controls.

*

P < 0.05;

**

P < 0.01.

***

P < 0.001 compared to oil-SHOVX;

P < 0.05;

††

P < 0.01;

†††

P < 0.001 compared to oil-OVXE2;

P < 0.05 compared to TP-OVXE2 rats.