Figure 2. Inhibition of conducted vasodilatation during SNA is reversed through blockade of both α₁- and α₂-adrenoreceptors.

In each of these experiments, across 3 conditions (control, SNA, SNA + treatment), there was significant main effect of distance on conducted vasodilatation (2-way ANOVA). A, phentolamine restored conducted vasodilatation to ACh during 8 Hz SNA (n = 5; d.f. = 8, F = 7.366, P < 0.001). B, propranolol had no effect on conducted vasodilatation during SNA (n = 5; d.f. = 8, F = 9.398, P < 0.001). C, conduction during SNA was partially restored by prazosin (n = 5; d.f. = 8, F = 4.017, P = 0.004). D, conduction during SNA was partially restored by RX821002 (n = 5; d.f. = 8, F = 9.301, P < 0.001). Post hoc comparisons: *significant difference from control response at sites indicated (P < 0.05); ⁺significant difference from response during SNA at site indicated (P < 0.05).