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. 2005 Jan 13;563(Pt 3):843–854. doi: 10.1113/jphysiol.2004.074138

Figure 5. Effect of input conductance on persistent currents.

Figure 5

A, G93A low-input conductance (•) and high-input conductance (▴) motoneurones have a significantly larger PCNa than their control counterparts (low-input conductance, ○; high-input conductance ▵). Low input conductance: G93A, −125.88 ± 42.21 pA; control, −80.97 ± 42.76 pA; high input conductance: G93A, −132.88 ± 60.04 pA; control, −76.36 ± 45.15 pA. B, the G93A low-input conductance motoneurones had a significantly larger PCTTX-ins than the control sample, while the high-input conductance samples had similar values. Low input conductance: G93A, 52.70 ± 40.28 pA; control, 5.91 ± 56.55 pA; high input conductance: G93A, 39.26 ± 31.52 pA; control, 30.32 ± 49.9 pA. C, only the high-input conductance samples had a significant difference in total PC. The increased PC in the G93A sample was consistent with an increased neuronal excitability in high-input conductance G93A motoneurones. Low input conductance: G93A, −73.18 ± 50.44 pA; control, −75.06 ± 41.88 pA; high input conductance: G93A, −93.63 ± 70.11 pA; control, −46.04 ± 44.71 pA. In each panel *P < 0.05 and **P = 0.005.