Figure 4. Calculated RRP and p estimates are reliable.

A, eIPSC coefficient of variation (CV) was calculated using either recorded eIPSCs (CV =s.d. mean⁻¹) or obtained RRP and p values (CV = ((1 −p)/(RRP ×p))^1/2. The dashed line corresponds to a 1: 1 ratio. B, changes in the paired-pulse ratio (PPR, eIPSC₂/eIPSC₁) early during postnatal development. PPR at P1 was significantly smaller. C, there was no correlation between PPR and eIPSC decay kinetics. D, PPR and calculated release probabilities negatively correlated at all ages tested (only P1 and P22 shown).