Table 1.

Effect of PTH on osteoclast formation and bone resorption in iNOS-deficient and WT mice

Genotype	Treatment	Osteoclasts per well	Resorption, mm2
WT	Vehicle	78.7  ± 29.2	0.23  ± 0.07
WT	PTH	211.0  ± 80.9**	0.68  ± 0.12***
KO	Vehicle	86.5  ± 38.7	0.32  ± 0.11
KO	PTH	196.8  ± 65.8**	0.74  ± 0.21**

Cocultures were performed on dentine as described. PTH (4 × 10⁻⁸ M) or vehicle was added on day 7, and the cultures were terminated on day 10. Values are expressed as mean ± SD. **, P < 0.01; ***, P < 0.001; from vehicle; n = 6.