Table 3.

The effect of a higher protein intake on urea synthesis and the transfer of ¹⁵N from [5-¹⁵N]glutamine to urea

Subject category	Change in
	Urea flux, μmol/(kg⋅h)	Glutamine flux, μmol/(kg⋅h)
Healthy controls	+64  ± 7	+11  ± 26	−0.027  ± 0.02
ASSD heterozygous carriers	+58  ± 12	+7  ± 80	−0.017  ± 0.05
ASLD heterozygous carriers	+56  ± 3	+26  ± 16	−0.029  ± 0.013
Asymptomatic OTCD carriers	+44  ± 5*	−1  ± 5	−0.057  ± 0.006*

Significant difference from control values. *, P < 0.05.