Table 4.
Reversal of cell Na+/K+ content ratio |
High mean cell volume with wide range |
Low MCHC and cell density |
Large increase in passive fluxes of Na+ and K+ |
High-bumetanide (1 mM)-sensitive K+ flux component |
Very high Na+/K+ pump expression and activity |
Many RBCs with morphological features of ISC |
Low proportion of reticulocytes |
Average proportion about 4% of total SSRBCs |