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. 2006 Nov;174(3):1517–1528. doi: 10.1534/genetics.106.060723

TABLE 5.

Performance for models with nonuniform crossing over and uniform gene conversion with unphased data

γa ρa g(γ)b g(ρ)b B(γ)c B(ρ)c E(Inline graphic)d E(Inline graphic)d V(γ)e V(ρ)e
Hudson's composite-likelihood method
20 20 0.420 0.972 0.780 0.509 12.499 20.320 0.986 0.448
60 20 0.592 0.958 0.763 0.413 39.479 22.390 0.668 0.533
80 20 0.636 0.948 0.776 0.418 59.159 22.102 0.611 0.535
20 40 0.288 0.964 0.841 0.654 9.440 37.000 1.047 0.360
40 40 0.384 0.984 0.853 0.578 18.940 39.720 0.856 0.356
Summary statistics method
20 20 0.578 0.938 0.501 0.528 24.482 21.220 1.208 0.598
60 20 0.732 0.866 0.529 0.498 66.330 22.578 0.745 0.773
80 20 0.772 0.832 0.518 0.486 84.518 24.412 0.600 0.911
20 40 0.458 0.894 0.549 0.695 25.312 36.030 1.462 0.457
40 40 0.608 0.88 0.561 0.623 42.800 38.464 0.974 0.503
a

γ and ρ denote the true values of the gene-conversion and crossing-over rates under which 500 data sets were simulated.

b

g(γ) and g(ρ) denote the fraction of the data sets for which the estimates of gene conversion (Inline graphic) and crossing over (Inline graphic) lie within a factor of 2 of the true values (i.e., γ and ρ), respectively.

c

B(γ) and B(ρ) denote the fraction of times the estimates of gene conversion and crossing over are lower than the true values, given that they are not equal to the true values.

d

E(Inline graphic) and E(Inline graphic) denote the mean of the estimates of gene-conversion and crossing-over rates.

e

V(γ) and V(ρ) denote the root mean square relative error for the estimates.