TABLE 3.
Pearson correlation coefficient (r) of LD, R2, and D′ and distances of sites
|
r (Pearson correlation coefficient)
|
||||
|---|---|---|---|---|
| Region | Sites | No. | R2 | D′ |
| Exons 2–9 | Polymorphic | 51 | −0.13*** | −0.08 |
| Synonymous | 13 | −0.06 | −0.4** | |
| Exons 2–5 | Polymorphic | 17 | −0.5*** | −0.5*** |
| Synonymous | 4 | −0.7* | −0.97 | |
| Exons 6–9 | Polymorphic | 34 | −0.18*** | −0.09 |
| Synonymous | 7 | −0.37* | −0.56** | |
The analysis was performed on polymorphic and synonymous sites and on different parts of the sequence (coding sequence of exons 2–9, exons 2–5, exons 6–9). Only polymorphic sites that have a frequency >10% were included in the analysis. The significance of r was determined on the basis of 5000 random permutations of polymorphic sites. The type II sequence was not included in the analysis. *P < 0.05, **P < 0.01, ***P < 0.001.