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. 2006 Nov;174(3):1469–1480. doi: 10.1534/genetics.106.062018

TABLE 3.

Pearson correlation coefficient (r) of LD, R2, and D′ and distances of sites

r (Pearson correlation coefficient)
Region Sites No. R2 D
Exons 2–9 Polymorphic 51 −0.13*** −0.08
Synonymous 13 −0.06 −0.4**
Exons 2–5 Polymorphic 17 −0.5*** −0.5***
Synonymous 4 −0.7* −0.97
Exons 6–9 Polymorphic 34 −0.18*** −0.09
Synonymous 7 −0.37* −0.56**

The analysis was performed on polymorphic and synonymous sites and on different parts of the sequence (coding sequence of exons 2–9, exons 2–5, exons 6–9). Only polymorphic sites that have a frequency >10% were included in the analysis. The significance of r was determined on the basis of 5000 random permutations of polymorphic sites. The type II sequence was not included in the analysis. *P < 0.05, **P < 0.01, ***P < 0.001.