Molecular analysis of APR1 and SAT1. A, Genomic DNA was digested with BamHI, SalI, and HindIII singly and in combination, blotted onto a membrane, and hybridized with radioactively labeled APR1 cDNA. B, A restriction map of the genomic region containing the APR1 gene. The map was compiled from DNA gel blots using the 5′ and 3′ ends of the APR1 cDNA separately as hybridization probes. The 5′ probe contained cDNA sequences 5′ of the HindIII site designated in the map. The 3′ probe contained cDNA sequences 3′ of the HindIII site designated in the map. C, Genomic DNA was digested with BamHI, SalI, and HindIII singly and in combination, blotted onto a membrane, and hybridized with radioactively labeled SAT1 cDNA. D, A restriction map of the genomic region containing the SAT1 gene. The map was compiled from DNA gel blots using the 5′ and 3′ ends of the SAT1 cDNA separately as hybridization probes. The 5′ probe contained cDNA sequences 5′ of the BamHI site designated in the map. The 3′ probe contained cDNA sequences 3′ of the BamHI site designated in the map.