Skip to main content
. 2000 Jun 27;97(14):8116–8121. doi: 10.1073/pnas.140204597

Figure 1.

Figure 1

Contextual conditioning with a single training trial. (A) The freezing of one group of NT4−/− (n = 8) and wt (n = 8) mice during training. The solid line indicates the duration of the tone (CS). The arrow indicates the 2-s foot shock. ANOVA showed no significant difference between NT4−/− and wt mice (P = 0.31). The freezing responses of all other groups of mice for both context and cue conditioning tests are very similar to what is shown in A. (B–D) Three separate groups of NT4−/− and wt mice were tested for contextual conditioning at 30 min (B), 2 h (C), and 24 h (D) after training. ANOVA showed highly statistically significant differences between NT4−/− and wt mice at 2 and 24 h (P < 0.0001) but no significant difference at 30 min (P = 0.12).