Figure 2.

Blood pressure. (A) Mean arterial pressure (MAP) measured by carotid artery cannulation in conscious animals is not different between wild-type (+/+, n = 8) and B1-deficient mice (−/−, n = 8). (B) Blood pressure decline after i.p. injection of 250 μg/kg LPS in wild-type (+/+, n = 11) and B1-deficient mice (−/−, n = 9) is significantly different until 35 min after LPS administration but not thereafter. Data are means ± SEM and were analyzed by analysis of variance followed by Dunnetts' test. *, P < 0.05 compared with +/+ animals.