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Frameshift mutations at simple sequence repeats
| Genotype | Number of G418-resistant colonies/106 cells | |
|---|---|---|
| (G)10 repeata | (CA)15C repeatb | |
| WT pS | 0.75 (±0.0) | 83 (±22) |
| WT pS-MSH2 | 322 (±36) | 159 (±51) |
| Msh2+/− pS | ND | 44 (±13) |
| Msh2+/− pS-MSH2 | ND | 214 (±19) |
| Msh2−/− pS | 2285 (±1039) | 5085 (±1239) |
aResults from two independent experiments.
bResults from four independent experiments.
