TABLE 1.
IC50s and fold resistances for incorporation of CBV-TP and ddATP
| Type of RT | ddATP
|
CBV-TP
|
||
|---|---|---|---|---|
| IC50 (μM) | Fold resistance | IC50 (μM) | Fold resistance | |
| WT | 0.5 | 0.7 | ||
| 74V | 1 | 2 | 0.7 | |
| 184V | 1 | 2 | 0.7 | |
| 74V-184V | 3 | 6 | 7 | 10 |
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