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. 2006 Dec 1;2(12):e164. doi: 10.1371/journal.pcbi.0020164

Figure 2. Repetitive and Overlapping Binding Sites.

Figure 2

(A) Histogram of the number of binding sites responsible for each interaction between a TF and an operon, according to the EcoCyc database [8]. Note that multiple sites are common; the cis-regulatory region of focA, e.g., has as many as 11 binding sites for NarL.

(B) Histogram of the number of binding sites overlapping with each binding site [8]. For example, bin 1 with height 300 should be interpreted as: there are 300 binding sites that overlap with exactly one other binding site. Overlap is common; some ArcA sites in the sodA regulatory region overlap with as many as 11 sites.