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Immunodominant and subdominant SIV/SHIV epitopes have similar peptide binding affinities for MHC class I. (A) Peak tetramer responses for the dominant p11C and subdominant p68A epitopes in SIV-infected Mamu-A*01-positive rhesus monkeys. (B) Peak tetramer responses for the dominant p199RY and subdominant p56 epitopes in SIV-infected Mamu-A*02-positive monkeys. (C) Binding affinities of p11C and p68A for Mamu-A*01. (D) Binding affinities of p199RY and p56 for Mamu-A*02.
