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GBV-C MAbs used in this study
| Antibody | Competition group | Isotype | E2 bindinga | Polyclonal competition |
|---|---|---|---|---|
| M3 | Universal (U) | IgG2b(κ) | NS | No |
| M5 | I | IgG2b(λ) | D | Yes |
| M6 | II | IgG2a(κ) | NB | No |
| M11 | II | IgG1(κ) | NB | No |
| M13 | III | IgG2b(κ) | D | No |
| M17 | I | IgG1(κ) | D | Yes |
| M19 | III | IgG2b(κ) | D | No |
| M30 | IV | IgG2b(κ) | NS | No |
NS, nonspecific background; D, detects E2 bound to cells; NB, neutralizes binding of E2 to cells.
