Deletion of the N terminus of SCD inhibits the degradation of SCD-GFP constructs. (A) Fluorescence of SCD 27–358-GFP and SCD 45–358-GFP after cycloheximide treatment. The constructs localized to the ER remained fluorescent without relocalization to other cellular compartments. (B) A flow cytometric analysis of the fluorescence stabilities of SCD-GFP constructs with deleted N termini. After 48 h, the transfected cells were treated with cycloheximide for 0, 2, and 4 h. The treated cells were collected, and 10,000 cells were subjected to FACS analysis. The percentage of cells deemed fluorescent is indicated.