Skip to main content
The BMJ logoLink to The BMJ
. 1993 Oct 16;307(6910):972–977. doi: 10.1136/bmj.307.6910.972

Intensive Care Society's APACHE II study in Britain and Ireland--I: Variations in case mix of adult admissions to general intensive care units and impact on outcome.

K M Rowan 1, J H Kerr 1, E Major 1, K McPherson 1, A Short 1, M P Vessey 1
PMCID: PMC1679155  PMID: 8241908

Abstract

OBJECTIVES--To describe the extent of variation in the case mix of adult admissions to general intensive care units in Britain and Ireland and investigate the impact of such variation on outcome. DESIGN--Prospective, cohort study of consecutive admissions to intensive care units. SETTING--26 general intensive care units in Britain and Ireland. SUBJECTS--9099 admissions to the intensive care units studied. MAIN OUTCOME MEASURE--Death or survival at discharge before and after adjustment of case mix (age, history of chronic conditions, surgical status, diagnosis, and severity of illness) according to the APACHE II method. RESULTS--Important differences in case mix were found, with large variations between the units. Hospital mortality was significantly associated with most of the case mix factors investigated. CONCLUSIONS--Comparing crude death rates in hospital between intensive care units may be misleading indicators of performance. The collection of data on case mix needs to be standardised and differences in case mix adjusted for when comparing outcome between different intensive care units.

Full text

PDF
972

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bion J. F., Aitchison T. C., Edlin S. A., Ledingham I. M. Sickness scoring and response to treatment as predictors of outcome from critical illness. Intensive Care Med. 1988;14(2):167–172. doi: 10.1007/BF00257472. [DOI] [PubMed] [Google Scholar]
  2. Chisakuta A. M., Alexander J. P. Audit in intensive care. The APACHE II classification of severity of disease. Ulster Med J. 1990 Oct;59(2):161–167. [PMC free article] [PubMed] [Google Scholar]
  3. Dragsted L., Jörgensen J., Jensen N. H., Bönsing E., Jacobsen E., Knaus W. A., Qvist J. Interhospital comparisons of patient outcome from intensive care: importance of lead-time bias. Crit Care Med. 1989 May;17(5):418–422. doi: 10.1097/00003246-198905000-00008. [DOI] [PubMed] [Google Scholar]
  4. Draper E. A., Wagner D. P., Knaus W. A. The use of intensive care: a comparison of a university and community hospital. Health Care Financ Rev. 1981 Dec;3(2):49–64. [PMC free article] [PubMed] [Google Scholar]
  5. Eagle K. A., Mulley A. G., Field T. S., Skates S., Bero G., Clark C. E., Sexton J. O., Reder V. A., Berrigan G., Procaccini J. Variation in intensive care unit practices in two community hospitals. Med Care. 1991 Dec;29(12):1237–1245. doi: 10.1097/00005650-199112000-00006. [DOI] [PubMed] [Google Scholar]
  6. Gilbertson A. A., Smith J. M., Mostafa S. M. The cost of an intensive care unit: a prospective study. Intensive Care Med. 1991;17(4):204–208. doi: 10.1007/BF01709878. [DOI] [PubMed] [Google Scholar]
  7. Knaus W. A., Draper E. A., Wagner D. P., Zimmerman J. E. APACHE II: a severity of disease classification system. Crit Care Med. 1985 Oct;13(10):818–829. [PubMed] [Google Scholar]
  8. Knaus W. A., Draper E. A., Wagner D. P., Zimmerman J. E. An evaluation of outcome from intensive care in major medical centers. Ann Intern Med. 1986 Mar;104(3):410–418. doi: 10.7326/0003-4819-104-3-410. [DOI] [PubMed] [Google Scholar]
  9. Knaus W. A., Draper E. A., Wagner D. P., Zimmerman J. E., Birnbaum M. L., Cullen D. J., Kohles M. K., Shin B., Snyder J. V. Evaluating outcome from intensive care: a preliminary multihospital comparison. Crit Care Med. 1982 Aug;10(8):491–496. doi: 10.1097/00003246-198208000-00001. [DOI] [PubMed] [Google Scholar]
  10. Lemeshow S., Teres D., Avrunin J. S., Gage R. W. Refining intensive care unit outcome prediction by using changing probabilities of mortality. Crit Care Med. 1988 May;16(5):470–477. doi: 10.1097/00003246-198805000-00002. [DOI] [PubMed] [Google Scholar]
  11. Lemeshow S., Teres D., Pastides H., Avrunin J. S., Steingrub J. S. A method for predicting survival and mortality of ICU patients using objectively derived weights. Crit Care Med. 1985 Jul;13(7):519–525. doi: 10.1097/00003246-198507000-00001. [DOI] [PubMed] [Google Scholar]
  12. Mahul P., Perrot D., Tempelhoff G., Gaussorgues P., Jospe R., Ducreux J. C., Dumont A., Motin J., Auboyer C., Robert D. Short- and long-term prognosis, functional outcome following ICU for elderly. Intensive Care Med. 1991;17(1):7–10. doi: 10.1007/BF01708401. [DOI] [PubMed] [Google Scholar]
  13. Marks R. J., Simons R. S., Blizzard R. A., Browne D. R. Predicting outcome in intensive therapy units--a comparison of Apache II with subjective assessments. Intensive Care Med. 1991;17(3):159–163. doi: 10.1007/BF01704720. [DOI] [PubMed] [Google Scholar]
  14. Marsh H. M., Krishan I., Naessens J. M., Strickland R. A., Gracey D. R., Campion M. E., Nobrega F. T., Southorn P. A., McMichan J. C., Kelly M. P. Assessment of prediction of mortality by using the APACHE II scoring system in intensive-care units;. Mayo Clin Proc. 1990 Dec;65(12):1549–1557. doi: 10.1016/s0025-6196(12)62188-0. [DOI] [PubMed] [Google Scholar]
  15. Ridley S., Jackson R., Findlay J., Wallace P. Long term survival after intensive care. BMJ. 1990 Nov 17;301(6761):1127–1130. doi: 10.1136/bmj.301.6761.1127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Shiell A. M., Griffiths R. D., Short A. I., Spiby J. An evaluation of the costs and outcome of adult intensive care in two units in the UK. Clin Intensive Care. 1990;1(6):256–262. [PubMed] [Google Scholar]
  17. Teasdale G., Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974 Jul 13;2(7872):81–84. doi: 10.1016/s0140-6736(74)91639-0. [DOI] [PubMed] [Google Scholar]
  18. Waters M., Nightingale P., Edwards J. D. A critical study of the APACHE II scoring system using earlier data collection. Arch Emerg Med. 1990 Mar;7(1):16–20. doi: 10.1136/emj.7.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from BMJ : British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES