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. 2006 Dec;17(12):5163–5172. doi: 10.1091/mbc.E06-04-0320

Figure 4.

Figure 4.

Wnt5a participates in capillary-like networks of endothelial cells and endothelial cell migration. (A) Retroviral-infected HUVEC either overexpressing Wnt5a-HA, compared with control (HA), showed enhanced formation of networks (top pictures). HUVEC overexpressing shRNA to target Wnt5a gene expression showed reduced ability to form networks when compared with control shRNA cells. (B) Retroviral infected HUVEC overexpressing shRNA targeting Wnt5a gene expression showed reduced ability to migrate, measured 10 h after a wound was made on a confluent plate, when compared with control cells. A representative experiment is shown. Black bars indicate cell front.