Table 2.
Domain profile of MASC—10 most common
| Domain | Accession | % MASC a | % Proteome b | Ratio c |
|---|---|---|---|---|
| Protein kinase | IPR000719 | 11.8 | 3.75 | 3.16 |
| Serine/threonine protein kinase | IPR002290 | 10.2 | 1.69 | 6.05 |
| SH3 | IPR001452 | 8.06 | 1.51 | 5.33 |
| Pleckstrin-like | IPR001849 | 5.91 | 1.25 | 4.72 |
| PDZ/DHR/GLGF | IPR001478 | 5.91 | 0.74 | 8.04 |
| Small GTP-binding protein domain | IPR005225 | 5.38 | 1.49 | 3.62 |
| Pleckstrin homology-type | IPR011993 | 4.84 | 1.08 | 4.49 |
| Calcium-binding EF-hand | IPR002048 | 4.84 | 1.65 | 2.93 |
| C2 | IPR000008 | 4.84 | 0.82 | 5.92 |
| IQ calmodulin-binding region | IPR000048 | 3.76 | 0.31 | 12.0 |
aPercentage of MASC proteins possessing domain annotation.
bPercentage of mouse proteome possessing domain annotation.
cRatio of MASC to proteome (measure of enrichment in MASC).