Table 7.
Significant motif pairs from different phases (time points) of cell cycle
| Significant pair | P-value | Time (h) | Phase | Experimental evidence (PubMed ID) |
|---|---|---|---|---|
| Oct-1*NF-Y | 8.0 × 10−9 | 6 | G1 | 14586402 |
| MEF-2*E2F-1 | 5.6 × 10−15 | 24 | G1 | 11027611 |
| TBP*AREB6 | 1.2 × 10−3 | 8 | G1/S | 14761964 |
| E2F*E2F-4/DP-2 | 1.3 × 10−15 | 10 | G1/S | 9372931 |
| E2F(M00050)*E2F(M00516) | 1.3 × 10−15 | 10 | G1/S | 15014447 |
| AML1*E2F-4/DP-2 | 1.0 × 10−10 | 10 | G1/S | — |
| AML1*E2F | 2.6 × 10−5 | 10 | G1/S | 8834231 |
| AhR*E2F | 7.3 × 10−5 | 0 | G2/M | 10644764 |
| E2F*E2F-1/DP-1 | 9.7 × 10−9 | 18 | G2/M | 7917337 |
| E2F-1/DP-1*Ik-3 | 9.7 × 10−9 | 18 | G2/M | — |
| E2F-1/DP-1*Oct-1 | 2.8 × 10−7 | 18 | G2/M | 10662552 |
| E2F*Ik-3 | 5.1 × 10−7 | 18 | G2/M | — |
The experimental evidence reported in the literature for activity of a given motif pair during cell cycle is included in the last column. Italicized Pubmed IDs indicate indirect evidence.