Table.
Summary of Reported Cases of Necrotizing Myositis*
| Author | Year | Age/Sex† | Meds‡ | Site§ | Abx¶ | Surg‖ | Death | Micro£ |
|---|---|---|---|---|---|---|---|---|
| Barrett | 1958 | 33/M | Z | lLE | pcn | Y | Y | GABHS |
| Svane | 1971 | 32/M | U | Glu | pcn | Y | Y | GABHS |
| 30/M | U | Pec | none | N | Y | GABHS | ||
| Chambers | 1974 | 18/M | Z | rLE | cph, stp | Y | N | PS, BS |
| Mac Laurin | 1977 | 49/F | U | UE | pcn | Y | Y | GABHS |
| Aitken | 1982 | 69/F | U | LE | U | U | Y | Stp |
| 40/F | U | UE | U | U | Y | Stp | ||
| 49/M | U | LE | U | Y | N | Stp | ||
| 39/M | U | LE | U | Y | N | Stp | ||
| 81/M | U | LE | U | Y | Y | Stp | ||
| Adams | 1985 | 53/M | Z | lLE | pcn, mth, gen | Y | Y | GABHS |
| 40/F | Z | lLE | pcn, chl | Y | Y | GABHS | ||
| Nather | 1985 | 11/M | Z | Hip | pcn | Y | N | GABHS |
| 22/F | Z | Abd | pcn | Y | N | Stp | ||
| Jansen | 1988 | 39/M | Z | lLE | amp, gen, mtr | Y | N | GABHS |
| Doebbeling | 1989 | 76/M | S | rUE | pcn, gen, van | Y | N | GABHS |
| Schattner | 1989 | 70/F | Z | rLE | cez, gen | N | Y | GABHS |
| Boyle | 1992 | 12/M | N | rLE | amp, cef, naf | Y | N | GABHS |
| James | 1992 | 60/F | Z | Thx | U | N | Y | GABHS, SA |
| Hird | 1994 | 17/M | N | rLE | pcn | Y | N | GABHS |
| Marck | 1996 | 36/M | S | lUE | pcn, flu, gen | Y | N | GABHS |
| Wagner | 1996 | 64/F | N | rLE | brd | N | Y | GGS |
| Kang | 1998 | 33/M | N | rLE | U | Y | N | Stp |
| Tang | 2001 | 5/F | Z | Hip | amx/cla, cli | Y | N | GABHS |
| Baevsky | 2005 | 8/F | NCIS | T | cli | Y | N | GABHS |
Summary of the English MEDLINE cases of necrotizing myositis, defined as infectious muscle necrosis with noninvolvement of adjacent fascia and lacking any abscess formation.
Age (yrs); M = male, F = female
Immunosuppressant medication use at time of diagnosis: S = Steroids; N = NSAID; C = COX-2 inhibitor; U = unknown use; I = immunomodulator (infliximab); Z = none
Site of infection: Abd = abdomen; Glu = buttocks; Hip = hip; LE = lower extremity; Pec = pectoralis; T = tongue; Thx = thorax; UE = upper extremity; r = right; l = left
Antibiotic administered: U = unknown; amp = ampicillin; amx = amoxicillin; brd = broad spectrum (unspecified); cef = cefuroxime; cez = cephazolin; chl = chloramphenicol; cla = clavulanate; cli = clindamycin; cph = cephalothin; flu = flucloxacillin; gen = gentamicin; mth = methicillin; mtr = metronidazole; naf = nafcillin; pcn = penicillin; stp = streptomycin; van = vancomycin
Surgical intervention: Y = yes; N = no; U = data unavailable
Microbial organism(s): BS = Bacteroides subtilis; GABHS = Group A beta-hemolytic streptococcus; GGS = Group G streptococcus; PS = Peptostreptococcus; SA = Staphylococcus aureus; Stp = Streptococcus (not otherwise specified)