Table 3.

Reporter vector expression in long-term reconstituted mice

Vector, number	Copy number*	Hematopoietic tissues, % GFP+†			Marrow progenitor colonies
		WBC	Spleen	Marrow	% G418r‡	% GFP+	Variegation§
MGPN2, n = 8	0.4  ± 0.2	2  ± 3	1  ± 1	1  ± 1	6  ± 16	3  ± 2	Not determined
INS4 (+), n = 9	1.0  ± 0.3	19  ± 15	12  ± 7	16  ± 11	45  ± 20	18  ± 9	9 of 23

^*Provirus copy number estimated by Southern blot analysis of at time of death. 

^†Percent GFP⁺ cells determined by flow cytometry. 

^‡Percent G418^r colonies = (colony count + G418)/[colony count − G418] × 100. 

^§Defined by lack of GFP expression in most or all of cells in individual colonies analyzed after G418 selection.