Table 3.

Effects of haloperidol on the mC content of leukocyte, brain, and liver DNA

		mC content (mean ± SD)
Sex	Treatmenta	Leukocytes	P	Brain	P	Liver	P
Male	Haloperidol	3.817 ± 0.036	0.212	3.632 ± 0.047	0.273	3.445 ± 0.027	0.013
	Placebob	3.843 ± 0.042		3.650 ± 0.023		3.412 ± 0.033
Female	Haloperidol	3.812 ± 0.050	0.064	3.615 ± 0.031	0.026	3.449 ± 0.055	0.089
	Placebob	3.771 ± 0.048		3.652 ± 0.031		3.426 ± 0.027

^aEach treatment-group consisted of 10 rats.

^binjected with solvent, NaOH-buffered acetic acid (pH6.0), alone.

Differences in mean mC content between haloperidol- and placebo-treated groups were evaluated with the Mann-Whitney U test.